ANTHRACYCLINE DERIVATIVES AND THEIR USE AS CYTOSTATICS

The present invention relates to the micro-organism Streptomyces purpurascens (DSM 2658), its mutants and variants, a process for the preparation of anthracycline derivatives by fermentation of these cultures and to the anthracycline derivatives themselves. The new compounds are distinguished by ant...

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Hauptverfasser: FEHLHABER HANS-WOLFRAM, HUBER GERHARD, SEDLACEK HANS-HARALD, GAUKNAPILLI CHANDRASEKHAR REDDY, RATAN SAGAR SOOD, GANDHI JULIA, KRAEMER HANS PETER, BIMAL NARESH GANGULI, ARETZ WERNER, BERSCHEID HANS GERD
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to the micro-organism Streptomyces purpurascens (DSM 2658), its mutants and variants, a process for the preparation of anthracycline derivatives by fermentation of these cultures and to the anthracycline derivatives themselves. The new compounds are distinguished by antibacterial activity and, in addition, they act against various types of tumors.