PROCESS OF PRODUCING Sindora supa ANTI-DIABETES DRUG
The present utility model relates in general to a process of producing an herbal supplement for the prevention of diabetes mellitus. Specifically, it relates to the use of Sindora supa (S. supa) in producing a stable and standardized tablet dosage form of an anti-diabetes drug through alpha-glucosid...
Gespeichert in:
Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | ALTO, Philip Reginald C YU, Raymond Fernando B QUIBIN, Razile Kay A DE LOS SANTOS, Mark Gabriel M CATAP, Elena AMOR, Evangeline C BALOTRO, Bienvenido S SANCHEZ, Arlyn C BALANAY, Rua Marie F REGUNTON, Precious Caree V ALVARADO, Jowela B VILLONES, Lareno Jr. L JACINTO, Sonia PEREDAS, Charmaine R COTAS, Joyce Katherine P FERNANDEZ, Patrick YERRO, Jennylyn Z NAVARRO, Anna Isabel MORALES, John Perry C |
description | The present utility model relates in general to a process of producing an herbal supplement for the prevention of diabetes mellitus. Specifically, it relates to the use of Sindora supa (S. supa) in producing a stable and standardized tablet dosage form of an anti-diabetes drug through alpha-glucosidase inhibiting activity. The anti-diabetes drug composition comprises of: approximately 44-49 pcnt weight Sindora supa ethanolic extract; approximately 44-49 pcnt weight diluent preferably colloidal silica; approximately 1.78-1.96 pcnt weight disintegrant preferably crospovidone; approximately 4.44-4.90 pcnt binder preferably microcrystalline cellulose; and, approximately 0.45-0.49 pcnt flow activator preferably magnesium stearate. It is made by a process comprising: collecting and preparing raw materials; drying and milling the raw materials; subjecting the raw materials to ethanolic extraction; subjecting the ethanolic extract solution to rotary evaporation; subjecting the ethanolic extract to lyophilization; subjecting the ethanolic extract to quality control; conducting pre-formulation tests; dissolving the ethanolic extract in equal amounts of ethanol and colloidal silica; drying and sieving the silicated extract; mixing the silicated extract with microcrystalline cellulose, crospovidone, and magnesium stearate; subjecting the mixture to dry granulation; sieving and weighing the granular mixture; compressing the granular mixture into tablet dosage form; and, subjecting the tablets to quality control tests. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_PH22020050513UU1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>PH22020050513UU1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_PH22020050513UU13</originalsourceid><addsrcrecordid>eNrjZDAJCPJ3dg0OVvB3UwAyXUKdPf3cFYIz81LyixIViksLEhUc_UI8dV08HZ1cQ1yDFVyCQt15GFjTEnOKU3mhNDeDqptriLOHbmpBfnxqcUFicmpeakl8gIeRkYGRgYGpgamhcWiooTGx6gCYMSqB</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS OF PRODUCING Sindora supa ANTI-DIABETES DRUG</title><source>esp@cenet</source><creator>ALTO, Philip Reginald C ; YU, Raymond Fernando B ; QUIBIN, Razile Kay A ; DE LOS SANTOS, Mark Gabriel M ; CATAP, Elena ; AMOR, Evangeline C ; BALOTRO, Bienvenido S ; SANCHEZ, Arlyn C ; BALANAY, Rua Marie F ; REGUNTON, Precious Caree V ; ALVARADO, Jowela B ; VILLONES, Lareno Jr. L ; JACINTO, Sonia ; PEREDAS, Charmaine R ; COTAS, Joyce Katherine P ; FERNANDEZ, Patrick ; YERRO, Jennylyn Z ; NAVARRO, Anna Isabel ; MORALES, John Perry C</creator><creatorcontrib>ALTO, Philip Reginald C ; YU, Raymond Fernando B ; QUIBIN, Razile Kay A ; DE LOS SANTOS, Mark Gabriel M ; CATAP, Elena ; AMOR, Evangeline C ; BALOTRO, Bienvenido S ; SANCHEZ, Arlyn C ; BALANAY, Rua Marie F ; REGUNTON, Precious Caree V ; ALVARADO, Jowela B ; VILLONES, Lareno Jr. L ; JACINTO, Sonia ; PEREDAS, Charmaine R ; COTAS, Joyce Katherine P ; FERNANDEZ, Patrick ; YERRO, Jennylyn Z ; NAVARRO, Anna Isabel ; MORALES, John Perry C</creatorcontrib><description>The present utility model relates in general to a process of producing an herbal supplement for the prevention of diabetes mellitus. Specifically, it relates to the use of Sindora supa (S. supa) in producing a stable and standardized tablet dosage form of an anti-diabetes drug through alpha-glucosidase inhibiting activity. The anti-diabetes drug composition comprises of: approximately 44-49 pcnt weight Sindora supa ethanolic extract; approximately 44-49 pcnt weight diluent preferably colloidal silica; approximately 1.78-1.96 pcnt weight disintegrant preferably crospovidone; approximately 4.44-4.90 pcnt binder preferably microcrystalline cellulose; and, approximately 0.45-0.49 pcnt flow activator preferably magnesium stearate. It is made by a process comprising: collecting and preparing raw materials; drying and milling the raw materials; subjecting the raw materials to ethanolic extraction; subjecting the ethanolic extract solution to rotary evaporation; subjecting the ethanolic extract to lyophilization; subjecting the ethanolic extract to quality control; conducting pre-formulation tests; dissolving the ethanolic extract in equal amounts of ethanol and colloidal silica; drying and sieving the silicated extract; mixing the silicated extract with microcrystalline cellulose, crospovidone, and magnesium stearate; subjecting the mixture to dry granulation; sieving and weighing the granular mixture; compressing the granular mixture into tablet dosage form; and, subjecting the tablets to quality control tests.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201120&DB=EPODOC&CC=PH&NR=22020050513U1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201120&DB=EPODOC&CC=PH&NR=22020050513U1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ALTO, Philip Reginald C</creatorcontrib><creatorcontrib>YU, Raymond Fernando B</creatorcontrib><creatorcontrib>QUIBIN, Razile Kay A</creatorcontrib><creatorcontrib>DE LOS SANTOS, Mark Gabriel M</creatorcontrib><creatorcontrib>CATAP, Elena</creatorcontrib><creatorcontrib>AMOR, Evangeline C</creatorcontrib><creatorcontrib>BALOTRO, Bienvenido S</creatorcontrib><creatorcontrib>SANCHEZ, Arlyn C</creatorcontrib><creatorcontrib>BALANAY, Rua Marie F</creatorcontrib><creatorcontrib>REGUNTON, Precious Caree V</creatorcontrib><creatorcontrib>ALVARADO, Jowela B</creatorcontrib><creatorcontrib>VILLONES, Lareno Jr. L</creatorcontrib><creatorcontrib>JACINTO, Sonia</creatorcontrib><creatorcontrib>PEREDAS, Charmaine R</creatorcontrib><creatorcontrib>COTAS, Joyce Katherine P</creatorcontrib><creatorcontrib>FERNANDEZ, Patrick</creatorcontrib><creatorcontrib>YERRO, Jennylyn Z</creatorcontrib><creatorcontrib>NAVARRO, Anna Isabel</creatorcontrib><creatorcontrib>MORALES, John Perry C</creatorcontrib><title>PROCESS OF PRODUCING Sindora supa ANTI-DIABETES DRUG</title><description>The present utility model relates in general to a process of producing an herbal supplement for the prevention of diabetes mellitus. Specifically, it relates to the use of Sindora supa (S. supa) in producing a stable and standardized tablet dosage form of an anti-diabetes drug through alpha-glucosidase inhibiting activity. The anti-diabetes drug composition comprises of: approximately 44-49 pcnt weight Sindora supa ethanolic extract; approximately 44-49 pcnt weight diluent preferably colloidal silica; approximately 1.78-1.96 pcnt weight disintegrant preferably crospovidone; approximately 4.44-4.90 pcnt binder preferably microcrystalline cellulose; and, approximately 0.45-0.49 pcnt flow activator preferably magnesium stearate. It is made by a process comprising: collecting and preparing raw materials; drying and milling the raw materials; subjecting the raw materials to ethanolic extraction; subjecting the ethanolic extract solution to rotary evaporation; subjecting the ethanolic extract to lyophilization; subjecting the ethanolic extract to quality control; conducting pre-formulation tests; dissolving the ethanolic extract in equal amounts of ethanol and colloidal silica; drying and sieving the silicated extract; mixing the silicated extract with microcrystalline cellulose, crospovidone, and magnesium stearate; subjecting the mixture to dry granulation; sieving and weighing the granular mixture; compressing the granular mixture into tablet dosage form; and, subjecting the tablets to quality control tests.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAJCPJ3dg0OVvB3UwAyXUKdPf3cFYIz81LyixIViksLEhUc_UI8dV08HZ1cQ1yDFVyCQt15GFjTEnOKU3mhNDeDqptriLOHbmpBfnxqcUFicmpeakl8gIeRkYGRgYGpgamhcWiooTGx6gCYMSqB</recordid><startdate>20201120</startdate><enddate>20201120</enddate><creator>ALTO, Philip Reginald C</creator><creator>YU, Raymond Fernando B</creator><creator>QUIBIN, Razile Kay A</creator><creator>DE LOS SANTOS, Mark Gabriel M</creator><creator>CATAP, Elena</creator><creator>AMOR, Evangeline C</creator><creator>BALOTRO, Bienvenido S</creator><creator>SANCHEZ, Arlyn C</creator><creator>BALANAY, Rua Marie F</creator><creator>REGUNTON, Precious Caree V</creator><creator>ALVARADO, Jowela B</creator><creator>VILLONES, Lareno Jr. L</creator><creator>JACINTO, Sonia</creator><creator>PEREDAS, Charmaine R</creator><creator>COTAS, Joyce Katherine P</creator><creator>FERNANDEZ, Patrick</creator><creator>YERRO, Jennylyn Z</creator><creator>NAVARRO, Anna Isabel</creator><creator>MORALES, John Perry C</creator><scope>EVB</scope></search><sort><creationdate>20201120</creationdate><title>PROCESS OF PRODUCING Sindora supa ANTI-DIABETES DRUG</title><author>ALTO, Philip Reginald C ; YU, Raymond Fernando B ; QUIBIN, Razile Kay A ; DE LOS SANTOS, Mark Gabriel M ; CATAP, Elena ; AMOR, Evangeline C ; BALOTRO, Bienvenido S ; SANCHEZ, Arlyn C ; BALANAY, Rua Marie F ; REGUNTON, Precious Caree V ; ALVARADO, Jowela B ; VILLONES, Lareno Jr. L ; JACINTO, Sonia ; PEREDAS, Charmaine R ; COTAS, Joyce Katherine P ; FERNANDEZ, Patrick ; YERRO, Jennylyn Z ; NAVARRO, Anna Isabel ; MORALES, John Perry C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PH22020050513UU13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ALTO, Philip Reginald C</creatorcontrib><creatorcontrib>YU, Raymond Fernando B</creatorcontrib><creatorcontrib>QUIBIN, Razile Kay A</creatorcontrib><creatorcontrib>DE LOS SANTOS, Mark Gabriel M</creatorcontrib><creatorcontrib>CATAP, Elena</creatorcontrib><creatorcontrib>AMOR, Evangeline C</creatorcontrib><creatorcontrib>BALOTRO, Bienvenido S</creatorcontrib><creatorcontrib>SANCHEZ, Arlyn C</creatorcontrib><creatorcontrib>BALANAY, Rua Marie F</creatorcontrib><creatorcontrib>REGUNTON, Precious Caree V</creatorcontrib><creatorcontrib>ALVARADO, Jowela B</creatorcontrib><creatorcontrib>VILLONES, Lareno Jr. L</creatorcontrib><creatorcontrib>JACINTO, Sonia</creatorcontrib><creatorcontrib>PEREDAS, Charmaine R</creatorcontrib><creatorcontrib>COTAS, Joyce Katherine P</creatorcontrib><creatorcontrib>FERNANDEZ, Patrick</creatorcontrib><creatorcontrib>YERRO, Jennylyn Z</creatorcontrib><creatorcontrib>NAVARRO, Anna Isabel</creatorcontrib><creatorcontrib>MORALES, John Perry C</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ALTO, Philip Reginald C</au><au>YU, Raymond Fernando B</au><au>QUIBIN, Razile Kay A</au><au>DE LOS SANTOS, Mark Gabriel M</au><au>CATAP, Elena</au><au>AMOR, Evangeline C</au><au>BALOTRO, Bienvenido S</au><au>SANCHEZ, Arlyn C</au><au>BALANAY, Rua Marie F</au><au>REGUNTON, Precious Caree V</au><au>ALVARADO, Jowela B</au><au>VILLONES, Lareno Jr. L</au><au>JACINTO, Sonia</au><au>PEREDAS, Charmaine R</au><au>COTAS, Joyce Katherine P</au><au>FERNANDEZ, Patrick</au><au>YERRO, Jennylyn Z</au><au>NAVARRO, Anna Isabel</au><au>MORALES, John Perry C</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS OF PRODUCING Sindora supa ANTI-DIABETES DRUG</title><date>2020-11-20</date><risdate>2020</risdate><abstract>The present utility model relates in general to a process of producing an herbal supplement for the prevention of diabetes mellitus. Specifically, it relates to the use of Sindora supa (S. supa) in producing a stable and standardized tablet dosage form of an anti-diabetes drug through alpha-glucosidase inhibiting activity. The anti-diabetes drug composition comprises of: approximately 44-49 pcnt weight Sindora supa ethanolic extract; approximately 44-49 pcnt weight diluent preferably colloidal silica; approximately 1.78-1.96 pcnt weight disintegrant preferably crospovidone; approximately 4.44-4.90 pcnt binder preferably microcrystalline cellulose; and, approximately 0.45-0.49 pcnt flow activator preferably magnesium stearate. It is made by a process comprising: collecting and preparing raw materials; drying and milling the raw materials; subjecting the raw materials to ethanolic extraction; subjecting the ethanolic extract solution to rotary evaporation; subjecting the ethanolic extract to lyophilization; subjecting the ethanolic extract to quality control; conducting pre-formulation tests; dissolving the ethanolic extract in equal amounts of ethanol and colloidal silica; drying and sieving the silicated extract; mixing the silicated extract with microcrystalline cellulose, crospovidone, and magnesium stearate; subjecting the mixture to dry granulation; sieving and weighing the granular mixture; compressing the granular mixture into tablet dosage form; and, subjecting the tablets to quality control tests.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_PH22020050513UU1 |
source | esp@cenet |
subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PROCESS OF PRODUCING Sindora supa ANTI-DIABETES DRUG |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T04%3A18%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ALTO,%20Philip%20Reginald%20C&rft.date=2020-11-20&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EPH22020050513UU1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |