PROCESS OF PRODUCING Sindora supa ANTI-DIABETES DRUG
The present utility model relates in general to a process of producing an herbal supplement for the prevention of diabetes mellitus. Specifically, it relates to the use of Sindora supa (S. supa) in producing a stable and standardized tablet dosage form of an anti-diabetes drug through alpha-glucosid...
Gespeichert in:
Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The present utility model relates in general to a process of producing an herbal supplement for the prevention of diabetes mellitus. Specifically, it relates to the use of Sindora supa (S. supa) in producing a stable and standardized tablet dosage form of an anti-diabetes drug through alpha-glucosidase inhibiting activity. The anti-diabetes drug composition comprises of: approximately 44-49 pcnt weight Sindora supa ethanolic extract; approximately 44-49 pcnt weight diluent preferably colloidal silica; approximately 1.78-1.96 pcnt weight disintegrant preferably crospovidone; approximately 4.44-4.90 pcnt binder preferably microcrystalline cellulose; and, approximately 0.45-0.49 pcnt flow activator preferably magnesium stearate. It is made by a process comprising: collecting and preparing raw materials; drying and milling the raw materials; subjecting the raw materials to ethanolic extraction; subjecting the ethanolic extract solution to rotary evaporation; subjecting the ethanolic extract to lyophilization; subjecting the ethanolic extract to quality control; conducting pre-formulation tests; dissolving the ethanolic extract in equal amounts of ethanol and colloidal silica; drying and sieving the silicated extract; mixing the silicated extract with microcrystalline cellulose, crospovidone, and magnesium stearate; subjecting the mixture to dry granulation; sieving and weighing the granular mixture; compressing the granular mixture into tablet dosage form; and, subjecting the tablets to quality control tests. |
---|