BENZOBICYCLOALKANE AMINES

1363660 Benzobicycloalkanes AMERICAN HOME PRODUCTS CORP 1 Dec 1971 [3 Dec 1970 21 May 1971] 35390/73 Divided out of 1363658 Heading C2C Compounds of the general formula (W=O, NR6; m=0, 1; n=2-6; R=H, C 1-4 alkyl or alkoxy, OH, acyloxy, Ph(C 1-4 alkoxy), halogen, CF ; R7 = alkoxycarbonyl, C 1-4 alkyl...

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Hauptverfasser: FREND M, POTOSKI J
Format: Patent
Sprache:eng
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Zusammenfassung:1363660 Benzobicycloalkanes AMERICAN HOME PRODUCTS CORP 1 Dec 1971 [3 Dec 1970 21 May 1971] 35390/73 Divided out of 1363658 Heading C2C Compounds of the general formula (W=O, NR6; m=0, 1; n=2-6; R=H, C 1-4 alkyl or alkoxy, OH, acyloxy, Ph(C 1-4 alkoxy), halogen, CF ; R7 = alkoxycarbonyl, C 1-4 alkyl, C 3-5 alkenyl, CH 2 OH, Ph(C 1-4 alkyl); R6 = H, C 1-4 alkyl, Ph(C 1-4 alkyl), OH, alkoxy, provided that when R7=alkoxycarbonyl, R6 = OH or alkoxy; Ph = phenyl, optionally substituted) are prepared by cyclizing a compound of the formula (R8 = H, C 1-4 alkyl or alkoxy, acyloxy, Ph(C 1-4 alkoxy), halogen, CF ; Y = halogen, C 1-4 alkylsulphonyl, PhSO 2 ), optionally followed by conversion of R = alkoxy or Ph(alkoxy) to OH and/ or reaction with R6NH 2 . Certain of the ketones are characterized as semicarbazones.