ANTI-RABIES MONOCLONAL ANTIBODIES AND COCKTAIL THEREOF

The disclosure provides a murine monoclonal antibody capable of binding and neutralizing rabies or rabies related viruses. It also provides a cocktail of at least two monoclonal antibodies with said properties. The cocktail can neutralize the virus that is derived from species such as bats, dogs, co...

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Hauptverfasser: KALITA, Pankaj, BANDYOPADHYAY, Sanjay, KANSAGRA, Kevinkumar, MENDIRATTA, Sanjeev Kumar
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The disclosure provides a murine monoclonal antibody capable of binding and neutralizing rabies or rabies related viruses. It also provides a cocktail of at least two monoclonal antibodies with said properties. The cocktail can neutralize the virus that is derived from species such as bats, dogs, cows, mongooses, skunks, and wolves, and thus can be useful in treating a patient that has potentially been infected. Further, the disclosure provides a combination of muring monoclonal antibody or cocktail of at least two monoclonal antibodies and anti-rabies vaccine for use in post-exposure prophylaxis (PEP) with rabies or rabies-related viruses.