MODULATORS OF THE INTEGRATED STRESS PATHWAY

Provided herein are compounds, compositions, and methods useful for the modulation of elF2B, for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

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Bibliographische Detailangaben
Hauptverfasser:	SHI, Lei, MURAUSKI, Kathleen, XIONG, Zhaoming, SWEIS, Ramzi, Farah, DART, Michael, J, BROWN, Brian, S, BLACK, Lawrence, A, SIDRAUSKI, Carmela, CHUNG, Seungwon, TONG, Yunsong, PLIUSHCHEV, Marina, A, XU, Xiangdong, ZHANG, Qingwei, I, FROST, Jennifer, M, MARTIN, Kathleen, Ann
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are compounds, compositions, and methods useful for the modulation of elF2B, for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.