RNA MOLECULES
The present invention relates to new double stranded RNA (dsRNA) structures and their use in gene silencing. In one embodiment the dsRNA comprises a double hairpin (dumbbell) structure. In another embodiment a proportion of the sense and antisense strands of the dsRNA molecule contain ribonucleotide...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | DORAN, Timothy James GAO, Lingling WANG, Ming-Bo ALLU, Annapurna Devi DE FEYTER, Robert GREAVES, Ian Kevin SMITH, Neil Andrew TIZARD, Mark ANDERSON, Jonathan Paul ZHANG, Daai |
| description | The present invention relates to new double stranded RNA (dsRNA) structures and their use in gene silencing. In one embodiment the dsRNA comprises a double hairpin (dumbbell) structure. In another embodiment a proportion of the sense and antisense strands of the dsRNA molecule contain ribonucleotides that are either basepaired in a non-canonical basepair or are not basepaired. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_PH12020500527A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>PH12020500527A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_PH12020500527A13</originalsourceid><addsrcrecordid>eNrjZOAN8nNU8PX3cXUO9XEN5mFgTUvMKU7lhdLcDCpuriHOHrqpBfnxqcUFicmpeakl8QEehkYGRgamBgamRuaOhsZEKgMATdcdxA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>RNA MOLECULES</title><source>esp@cenet</source><creator>DORAN, Timothy James ; GAO, Lingling ; WANG, Ming-Bo ; ALLU, Annapurna Devi ; DE FEYTER, Robert ; GREAVES, Ian Kevin ; SMITH, Neil Andrew ; TIZARD, Mark ; ANDERSON, Jonathan Paul ; ZHANG, Daai</creator><creatorcontrib>DORAN, Timothy James ; GAO, Lingling ; WANG, Ming-Bo ; ALLU, Annapurna Devi ; DE FEYTER, Robert ; GREAVES, Ian Kevin ; SMITH, Neil Andrew ; TIZARD, Mark ; ANDERSON, Jonathan Paul ; ZHANG, Daai</creatorcontrib><description>The present invention relates to new double stranded RNA (dsRNA) structures and their use in gene silencing. In one embodiment the dsRNA comprises a double hairpin (dumbbell) structure. In another embodiment a proportion of the sense and antisense strands of the dsRNA molecule contain ribonucleotides that are either basepaired in a non-canonical basepair or are not basepaired.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210315&DB=EPODOC&CC=PH&NR=12020500527A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210315&DB=EPODOC&CC=PH&NR=12020500527A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DORAN, Timothy James</creatorcontrib><creatorcontrib>GAO, Lingling</creatorcontrib><creatorcontrib>WANG, Ming-Bo</creatorcontrib><creatorcontrib>ALLU, Annapurna Devi</creatorcontrib><creatorcontrib>DE FEYTER, Robert</creatorcontrib><creatorcontrib>GREAVES, Ian Kevin</creatorcontrib><creatorcontrib>SMITH, Neil Andrew</creatorcontrib><creatorcontrib>TIZARD, Mark</creatorcontrib><creatorcontrib>ANDERSON, Jonathan Paul</creatorcontrib><creatorcontrib>ZHANG, Daai</creatorcontrib><title>RNA MOLECULES</title><description>The present invention relates to new double stranded RNA (dsRNA) structures and their use in gene silencing. In one embodiment the dsRNA comprises a double hairpin (dumbbell) structure. In another embodiment a proportion of the sense and antisense strands of the dsRNA molecule contain ribonucleotides that are either basepaired in a non-canonical basepair or are not basepaired.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOAN8nNU8PX3cXUO9XEN5mFgTUvMKU7lhdLcDCpuriHOHrqpBfnxqcUFicmpeakl8QEehkYGRgamBgamRuaOhsZEKgMATdcdxA</recordid><startdate>20210315</startdate><enddate>20210315</enddate><creator>DORAN, Timothy James</creator><creator>GAO, Lingling</creator><creator>WANG, Ming-Bo</creator><creator>ALLU, Annapurna Devi</creator><creator>DE FEYTER, Robert</creator><creator>GREAVES, Ian Kevin</creator><creator>SMITH, Neil Andrew</creator><creator>TIZARD, Mark</creator><creator>ANDERSON, Jonathan Paul</creator><creator>ZHANG, Daai</creator><scope>EVB</scope></search><sort><creationdate>20210315</creationdate><title>RNA MOLECULES</title><author>DORAN, Timothy James ; GAO, Lingling ; WANG, Ming-Bo ; ALLU, Annapurna Devi ; DE FEYTER, Robert ; GREAVES, Ian Kevin ; SMITH, Neil Andrew ; TIZARD, Mark ; ANDERSON, Jonathan Paul ; ZHANG, Daai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PH12020500527A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2021</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>DORAN, Timothy James</creatorcontrib><creatorcontrib>GAO, Lingling</creatorcontrib><creatorcontrib>WANG, Ming-Bo</creatorcontrib><creatorcontrib>ALLU, Annapurna Devi</creatorcontrib><creatorcontrib>DE FEYTER, Robert</creatorcontrib><creatorcontrib>GREAVES, Ian Kevin</creatorcontrib><creatorcontrib>SMITH, Neil Andrew</creatorcontrib><creatorcontrib>TIZARD, Mark</creatorcontrib><creatorcontrib>ANDERSON, Jonathan Paul</creatorcontrib><creatorcontrib>ZHANG, Daai</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DORAN, Timothy James</au><au>GAO, Lingling</au><au>WANG, Ming-Bo</au><au>ALLU, Annapurna Devi</au><au>DE FEYTER, Robert</au><au>GREAVES, Ian Kevin</au><au>SMITH, Neil Andrew</au><au>TIZARD, Mark</au><au>ANDERSON, Jonathan Paul</au><au>ZHANG, Daai</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RNA MOLECULES</title><date>2021-03-15</date><risdate>2021</risdate><abstract>The present invention relates to new double stranded RNA (dsRNA) structures and their use in gene silencing. In one embodiment the dsRNA comprises a double hairpin (dumbbell) structure. In another embodiment a proportion of the sense and antisense strands of the dsRNA molecule contain ribonucleotides that are either basepaired in a non-canonical basepair or are not basepaired.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_PH12020500527A1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | RNA MOLECULES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T05%3A25%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DORAN,%20Timothy%20James&rft.date=2021-03-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EPH12020500527A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |