ANTICUERPOS ANTI-CALRETICULINA (CALR) MUTANTE Y USOS DE ESTOS

Se describen anticuerpos anti-calreticulina mutante (mutCALR). Tambien se describen acidos nucleicos, vectores, celulas, kits y composiciones farmaceuticas relacionadas. Tambien se describen metodos para tratar o diagnosticar neoplasias mieloproliferativas con los anticuerpos anti-mutCALR. Anti-muta...

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Hauptverfasser:	STEWART, Shaun M, BUONPANE, Rebecca A, ZHOU, Jing, LEI, Hsiang-Ting, NASTRI, Horacio G, REIS, Edimara S, ZHAO, Yonghong, CELIK, Hamza, DELLER, Marc C, MCQUIRTER, Leslie Brooke Epling, WASS, Brittney Melissa, MAYES, Patrick
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Se describen anticuerpos anti-calreticulina mutante (mutCALR). Tambien se describen acidos nucleicos, vectores, celulas, kits y composiciones farmaceuticas relacionadas. Tambien se describen metodos para tratar o diagnosticar neoplasias mieloproliferativas con los anticuerpos anti-mutCALR. Anti-mutant calreticulin (mutCALR) antibodies are disclosed. Also disclosed are related nucleic acids, vectors, cells, kits, and pharmaceutical compositions. Methods of treating or diagnosing myeloproliferative neoplasms with the anti-mutCALR antibodies are also disclosed.