COMPUESTOS DE CURCUMINA Y AMINOACIDOS BASICOS

La presente invencion se refiere a compuestos solidos cocristalinos y coamorfos formado por curcumina y L-arginina mediante enlaces no covalentes, que comprende proporciones molares de 5:1 a 1:5 de curcumina:L-arginina. Tambien se refiere a una composicion farmaceutica. Dichos compuestos solidos poseen propiedades fisicoquimicas mejoradas, tal como la solubilidad y permeabilidad, lo que repercute en mejores propiedades de biodisponibilidad, siendo util en el apoyo terapeutico como agente antioxidante, antiinflamatorio, analgesico, antitumoral y anticancerigeno. The present disclosure relates to: a solid compound formed by curcumin and arginine, which includes molar ratios between 5:1 and 1:5, with improved bioavailability properties, and which contains a solid compound comprising curcumin and arginine; the use thereof in complaints of inflammation, pain, stiffness and reduced range of movement, and in complaints that cause disability owing to the presentation of symptoms of pain, inflammation and stiffness and reduced range of movement, among others; and a pharmaceutical composition containing curcumin and L-arginine with a synergic effect in the therapeutic activity of the combination of curcumin and L-arginine, wherein the selected ratio allows a synergic effect in the therapeutic activity thereof to be obtained, and wherein an exemplary preferred ratio of curcumin to L-arginine is between 5:1 to 1:5.