COMPOSICION CON UN INHIBIDOR DE LA BOMBA DE PROTONES Y UN ANTAGONISTA H2

SE REFIERE A UNA COMBINACION DE FAMOTIDINA - DEXRABEPRAZOL O FAMOTIDINA - RABEPRAZOL. TAMBIEN SE REFIERE A PROCEDIMIENTOS PARA SU OBTENCION. DICHA COMBINACION ES SINERGICA, UTIL EN EL TRATAMIENTO DE ENFERMEDADES DE REFLUJO GASTROESOFAGICO. The present invention refers to an oral pharmaceutical composition comprising the combination of a proton-pump inhibitor and an H2 antagonist and the pharmaceutically acceptable salts thereof, additionally including pharmaceutically acceptable excipients or vehicles; as well as a process for the manufacture of a composition and use of the rabeprazole-famotidine or dexrabeprazole-famotidine combination with synergistic therapeutic activity indicated for treating gastroesophageal reflux, night acid reflux, peptic ulcer and/or eradication of H. pylori.