Substituted benzopyran analogs for the treatment of inflammation
A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A1, A2, A3, A4, R, R'', R1 and R2 are as de...
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| creator | OBUKOWICZ, MARK, G HANAU, CATHLEEN, E BROWN, DAVID, L CARTER, JEFFREY, S SRINIVASAN NAGARAJAN LUDWIG, CINDY, L SUZANNE METZ HARTMANN, SUSAN, J BALEKUDRU DEVADAS GRANETO, MATTHEW, J KORTE, DONALD, E BERTENSHAW, STEPHEN, R ROGIER, DONALD, J., JR |
| description | A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A1, A2, A3, A4, R, R'', R1 and R2 are as described in the specification. |
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Compounds of particular interest are defined by Formula I' wherein X, A1, A2, A3, A4, R, R'', R1 and R2 are as described in the specification.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060411&DB=EPODOC&CC=OA&NR=11912A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060411&DB=EPODOC&CC=OA&NR=11912A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OBUKOWICZ, MARK, G</creatorcontrib><creatorcontrib>HANAU, CATHLEEN, E</creatorcontrib><creatorcontrib>BROWN, DAVID, L</creatorcontrib><creatorcontrib>CARTER, JEFFREY, S</creatorcontrib><creatorcontrib>SRINIVASAN NAGARAJAN</creatorcontrib><creatorcontrib>LUDWIG, CINDY, L</creatorcontrib><creatorcontrib>SUZANNE METZ</creatorcontrib><creatorcontrib>HARTMANN, SUSAN, J</creatorcontrib><creatorcontrib>BALEKUDRU DEVADAS</creatorcontrib><creatorcontrib>GRANETO, MATTHEW, J</creatorcontrib><creatorcontrib>KORTE, DONALD, E</creatorcontrib><creatorcontrib>BERTENSHAW, STEPHEN, R</creatorcontrib><creatorcontrib>ROGIER, DONALD, J., JR</creatorcontrib><title>Substituted benzopyran analogs for the treatment of inflammation</title><description>A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. 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Compounds of particular interest are defined by Formula I' wherein X, A1, A2, A3, A4, R, R'', R1 and R2 are as described in the specification.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Substituted benzopyran analogs for the treatment of inflammation |
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