Substituted benzopyran derivatives for the treatment of inflammation

A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A1, A2, A3, A4, R, R'', R1 and R2 are as described in the specification.

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Bibliographische Detailangaben
Hauptverfasser:	OBUKOWICZ, MARK, G, NAGARAJAN, SRINIVASAN, R, TALLEY, JOHN, J, HANAU, CATHLEEN, E, BROWN, DAVID, L, CARTER, JEFFREY, S, CARTER, S. JEFFREY, LUDWIG, CINDY, L, SUZANNE METZ, HARTMANN, SUSAN, J, GRANETO, MATTHEW, J, BALEKUDRU DEVADAS, BERTENSHAW, STEPHEN, R, ROGIER, DONALD, J., JR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A1, A2, A3, A4, R, R'', R1 and R2 are as described in the specification.