Method for separating disodium 5'-inosinate

Provided is a method for separating disodium 5'-inosinate from a microorganism culturing medium containing same. In particular, provided is a method of separating disodium 5'-inosinate, the method comprising: culturing a microorganism that produces 5'-inosinic acid; adjusting the pH o...

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Hauptverfasser: Kim, Min Jong, Kim, Yu Shin, Kang, Seok Hyun, Kim, Jun Woo, Choi, Jung Hwa, Lim, Hwa Yeon, Kim, Il Chul, Oh, Chang Yub, Yu, Jae Hun
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creator Kim, Min Jong
Kim, Yu Shin
Kang, Seok Hyun
Kim, Jun Woo
Choi, Jung Hwa
Lim, Hwa Yeon
Kim, Il Chul
Oh, Chang Yub
Yu, Jae Hun
description Provided is a method for separating disodium 5'-inosinate from a microorganism culturing medium containing same. In particular, provided is a method of separating disodium 5'-inosinate, the method comprising: culturing a microorganism that produces 5'-inosinic acid; adjusting the pH of a culture broth of the microorganism to be from 7.4 to 8.0; concentrating the pH-adjusted culture broth to form disodium 5'-inosinate crystals; separating disodium 5'-inosinate crystals from the culture broth containing the disodium 5'-inosinate crystals; and washing the crystals by contacting the disodium 5'-inosinate crystals with a hydrophilic organic solvent.
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subjects CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title Method for separating disodium 5'-inosinate
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