Antiparasitic isoxazoline compounds, long-acting injectable formulations comprising them, methods and uses thereof

This invention relates to a long-acting injectable composition for the treatment or prevention of a parasitic infection or infestation comprising a compound of formula (Ie) and a carrier selected from one or more of ethanol, 1-propanol, isopropanol, a glycol ether, liquid PEG, a triglyceride, propyl...

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Bibliographische Detailangaben
Hauptverfasser:	Cheifetz, Peter, Meng, Charles, Le Hir De Fallois, Lois, Cady, Susan, Galeska, Izabela
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	This invention relates to a long-acting injectable composition for the treatment or prevention of a parasitic infection or infestation comprising a compound of formula (Ie) and a carrier selected from one or more of ethanol, 1-propanol, isopropanol, a glycol ether, liquid PEG, a triglyceride, propylene glycol, glycerol, a glycerol ester, benzyl benzoate, ethyl acetate, a cyclic carbonate, 2-pyrrolidone, N-methylpyrrolidone, dimethyl isosorbide (DMI), dimethylacetamide (DMA), dimethyl formamide (DMF), caprolactam, glycerol formal, acetone, dimethylsulfoxide (DMSO) and ethyl lactate. Also disclosed are further parasiticidal long-acting injectable compositions and new isoxazoline compounds.