Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof

Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof

The invention is related to multivalent immunogenic compositions comprising more than one S. pneumoniae polysaccharide protein conjugates, wherein each of the conjugates comprises a polysaccharide of a particular S. pneumoniae serotype conjugated to a carrier protein, wherein the S. pneumoniae serot...

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Hauptverfasser: He, Jian, Cui, Yadong Adam, Winters, Michael Albert, Smith, William, Abeygunawardana, Chitrananda, Skinner, Julie, Mchugh, Patrick, Musey, Luwy, Kosinski, Michael
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator He, Jian
Cui, Yadong Adam
Winters, Michael Albert
Smith, William
Abeygunawardana, Chitrananda
Skinner, Julie
Mchugh, Patrick
Musey, Luwy
Kosinski, Michael
description The invention is related to multivalent immunogenic compositions comprising more than one S. pneumoniae polysaccharide protein conjugates, wherein each of the conjugates comprises a polysaccharide of a particular S. pneumoniae serotype conjugated to a carrier protein, wherein the S. pneumoniae serotypes consist of 3, 7F, 19A, 22F, 33F, 6A, 15A, 16F, 23A, 23B, 24F, 31, 35B, 8, 9N, 10A, 11A, 12F, de-O-acetylated 15B or 15B or 15C, 17F, and 20A, and the carrier protein is CRM197.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
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