Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof

Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof

The invention is related to multivalent immunogenic compositions comprising more than one S. pneumoniae polysaccharide protein conjugates, wherein each of the conjugates comprises a polysaccharide of a particular S. pneumoniae serotype conjugated to a carrier protein, wherein the S. pneumoniae serot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: He, Jian, Cui, Yadong Adam, Winters, Michael Albert, Smith, William, Abeygunawardana, Chitrananda, Skinner, Julie, Mchugh, Patrick, Musey, Luwy, Kosinski, Michael
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention is related to multivalent immunogenic compositions comprising more than one S. pneumoniae polysaccharide protein conjugates, wherein each of the conjugates comprises a polysaccharide of a particular S. pneumoniae serotype conjugated to a carrier protein, wherein the S. pneumoniae serotypes consist of 3, 7F, 19A, 22F, 33F, 6A, 15A, 16F, 23A, 23B, 24F, 31, 35B, 8, 9N, 10A, 11A, 12F, de-O-acetylated 15B or 15B or 15C, 17F, and 20A, and the carrier protein is CRM197.