Anti-alpha synuclein antibodies

The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment...

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Hauptverfasser: Elliott, Peter Charles, Tyson, Kerry Louise, Kriek, Marco, Baker, Terence Seward, Lightwood, Daniel John, Downey, Patrick, De Lichtervelde, Lorenzo, Mcmillan, David James
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creator Elliott, Peter Charles
Tyson, Kerry Louise
Kriek, Marco
Baker, Terence Seward
Lightwood, Daniel John
Downey, Patrick
De Lichtervelde, Lorenzo
Mcmillan, David James
description The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Anti-alpha synuclein antibodies
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