Anti-alpha synuclein antibodies

The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Elliott, Peter Charles, Tyson, Kerry Louise, Kriek, Marco, Baker, Terence Seward, Lightwood, Daniel John, Downey, Patrick, De Lichtervelde, Lorenzo, Mcmillan, David James
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.