Acylated oxyntomodulin peptide analog

The present invention relates to a novel peptide analog of acylated oxyntomodulin and a pharmaceutical composition for preventing and treating obesity or overweightness, or diabetes accompanied by obesity and overweightness, containing the same, wherein the peptides have dual activation efficacy on...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Ryu, Chae-Lim, Chae, Yu-Na, Lee, Kyung-Seok, Im, Weon-Bin, Baek, Gye-Rim, Kim, Tae-Hyoung, Yang, Jae-Sung, Jung, Ill-Hun
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a novel peptide analog of acylated oxyntomodulin and a pharmaceutical composition for preventing and treating obesity or overweightness, or diabetes accompanied by obesity and overweightness, containing the same, wherein the peptides have dual activation efficacy on receptors of GLP-1/glucagon and increased in vivo half-life, which are superior to those of natural oxyntomodulin, and the pharmaceutical composition containing the same is effective in the treatment of metabolic diseases such as obesity and diabetes.