Nanopore sequencers

Nanopore sequencers including a cis well, a trans well, a membrane separating the cis well and the trans well, a nanopore inserted in the membrane, the nanopore fluidically connecting the cis well and the trans well, and a modified electrolyte in the trans well. The modified electrolyte includes a c...

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Bibliographische Detailangaben
Hauptverfasser: Mandell, Jeffrey G, Qiang, Liangliang, Akolkar, Rohan N, Fisher, Jeffrey S, Boyanov, Boyan, Barnard, Steven M
Format: Patent
Sprache:eng
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Zusammenfassung:Nanopore sequencers including a cis well, a trans well, a membrane separating the cis well and the trans well, a nanopore inserted in the membrane, the nanopore fluidically connecting the cis well and the trans well, and a modified electrolyte in the trans well. The modified electrolyte includes a cation and a cation complexing agent for complexing the cation (selected from calixarene, valinomycin, and derivatives thereof).