Primary carboxamides as btk inhibitors

Primary carboxamides as btk inhibitors

The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

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Bibliographische Detailangaben
Hauptverfasser: Osuma, Augustine, Wang, Zhi, Bonafoux, Dominique, Herold, J, Huntley, Raymond, Sheppard, George, Van Camp, Jennifer, Wallace, Grier, Davis, Heather, Somal, Gagandeep, Xu, Xiangdong, Friedman, Michael M, Vasudevan, Anil, Wilson, Noel, Van Epps, Stacy, Frank, Kristine, Wang, Lu, Hoemann, Michael
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.