Tetrasubstituted alkene compounds and their use

Disclosed herein are compounds of formulas (II) and (III), or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable sal...

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Hauptverfasser:	Zhu, Ping, Smith, Peter Gerard, Zheng, Guo Zhu, Wang, John, Bock, Mark, Hao, Ming-Hong, Puyang, Xiaoling, Nyavanandi, Vijay Kumar, Korpal, Manav, Samajdar, Susanta
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Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	Zhu, Ping Smith, Peter Gerard Zheng, Guo Zhu Wang, John Bock, Mark Hao, Ming-Hong Puyang, Xiaoling Nyavanandi, Vijay Kumar Korpal, Manav Samajdar, Susanta
description	Disclosed herein are compounds of formulas (II) and (III), or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.
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title	Tetrasubstituted alkene compounds and their use
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