Tetrasubstituted alkene compounds and their use

Disclosed herein are compounds of formulas (II) and (III), or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable sal...

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Bibliographische Detailangaben
Hauptverfasser:	Zhu, Ping, Smith, Peter Gerard, Zheng, Guo Zhu, Wang, John, Bock, Mark, Hao, Ming-Hong, Puyang, Xiaoling, Nyavanandi, Vijay Kumar, Korpal, Manav, Samajdar, Susanta
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Disclosed herein are compounds of formulas (II) and (III), or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.