Synthesis of polycyclic-carbamoylpyridone compounds
A synthetic method for preparing polycyclic-carbamoylpyridone compounds of Formula I where the bridged ring system is formed prior to a final hydroxyl deprotection step. A synthesis of Bictegravir is exemplified.
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| creator | Trinidad, Jonathan Ikemoto, Norihiro Griggs, Nolan Keaton, Katie Enquist, John Schrier, Kate Chiu, Anna Peng, Zhihui Herpt, Jochem Hale, Christopher Leeman, Michel Kraft, Matt Lazerwith, Scott Waltman, Andrew |
| description | A synthetic method for preparing polycyclic-carbamoylpyridone compounds of Formula I where the bridged ring system is formed prior to a final hydroxyl deprotection step. A synthesis of Bictegravir is exemplified. |
| format | Patent |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | Synthesis of polycyclic-carbamoylpyridone compounds |
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