Heterocyclic amides as kinase inhibitors

Disclosed are compounds having the formula: (I) wherein R1, R2, and R3 are as defined herein. The compounds as claimed are RIP1 kinase inhibitors and are used in the manufacture of a medicament to treat diseases and disorders associated with RIP1 kinase.

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Bibliographische Detailangaben
Hauptverfasser:	Sehon, Clark A, Daugan, Alain Claude-Marie, Harris, Philip Anthony, White, Gemma Victoria, Eidam, Patrick M, Anderson, Niall Andrew, Bandyopadhyay, Deepak, Donche, Frederic G, George, Nicolas S, King, Bryan W, Jeong, Jae U, Faucher, Nicolas Eric, Wisnoski, David Duff
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are compounds having the formula: (I) wherein R1, R2, and R3 are as defined herein. The compounds as claimed are RIP1 kinase inhibitors and are used in the manufacture of a medicament to treat diseases and disorders associated with RIP1 kinase.