Dosage regimen for madcam antagonists

The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.

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Hauptverfasser: Clare, Robert A, Tilley, Mera Krishnan, Ahmad, Alaa, Vincent, Michael Steven, Banerjee, Anindita, Von Schack, David J, Zhang, Weidong, Cataldi, Fabio, Comer, Gail M, Pradhan, Vivekananda, Page, Karen Michelle, Hassan-Zahraee, Mina
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creator Clare, Robert A
Tilley, Mera Krishnan
Ahmad, Alaa
Vincent, Michael Steven
Banerjee, Anindita
Von Schack, David J
Zhang, Weidong
Cataldi, Fabio
Comer, Gail M
Pradhan, Vivekananda
Page, Karen Michelle
Hassan-Zahraee, Mina
description The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Dosage regimen for madcam antagonists
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