Dosage regimen for madcam antagonists

The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.

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Bibliographische Detailangaben
Hauptverfasser:	Clare, Robert A, Tilley, Mera Krishnan, Ahmad, Alaa, Vincent, Michael Steven, Banerjee, Anindita, Von Schack, David J, Zhang, Weidong, Cataldi, Fabio, Comer, Gail M, Pradhan, Vivekananda, Page, Karen Michelle, Hassan-Zahraee, Mina
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.