Compositions for inhibiting masp-2 dependent complement activation

An isolated monoclonal antibody, or antigen-binding fragment thereof, that binds to human MASP-2, comprising a heavy chain variable region comprising the amino acid sequences set forth as amino acid residues 1 to 120 of SEQ ID NO:56, and a light chain variable region comprising the amino acid sequen...

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Hauptverfasser: Reiersen, Herald, Parent, James, Tedford, Clark, Kiprijanov, Sergej, Dudler, Thomas, Kavlie, Anita, Gombotz, Wayne, Hagemann, Urs
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creator Reiersen, Herald
Parent, James
Tedford, Clark
Kiprijanov, Sergej
Dudler, Thomas
Kavlie, Anita
Gombotz, Wayne
Hagemann, Urs
description An isolated monoclonal antibody, or antigen-binding fragment thereof, that binds to human MASP-2, comprising a heavy chain variable region comprising the amino acid sequences set forth as amino acid residues 1 to 120 of SEQ ID NO:56, and a light chain variable region comprising the amino acid sequences set forth as amino acid residues 146 to 250 of SEQ ID NO:56.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Compositions for inhibiting masp-2 dependent complement activation
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