Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease
The present disclosure relates to pharmaceutical compositions comprising a phosphorylated carbidopa prodrug and a phosphorylated L-dopa prodrug, and the use thereof in the treatment of Parkinson's disease and associated conditions.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Henry, Rodger F Ho, Raimundo Huang, Ye Dempah, Kassibla E Chan, Vincent S Cardinal-David, Benoit Wang, Zhi Zhang, Geoff G Stella, Valentino J Huters, Alexander D Krabbe, Scott W Lao, Yanbin Mayer, Peter T Enright, Brian P Lou, Xiaochun Mackey, Sean E Matulenko, Mark A Stambuli, James Miller, Christopher P Voight, Eric A Klix, Russell C Kym, Philip R |
| description | The present disclosure relates to pharmaceutical compositions comprising a phosphorylated carbidopa prodrug and a phosphorylated L-dopa prodrug, and the use thereof in the treatment of Parkinson's disease and associated conditions. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_NZ730996A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>NZ730996A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_NZ730996A3</originalsourceid><addsrcrecordid>eNrjZPBwTixKykzJL0hUSMxLUcjRBTMLivJTikrTi8FiJRmpmUUKpcWpCiX5CiVFqYklCgWJRdmZecX5eerFCimZxamJxak8DKxpiTnFqbxQmptBzs01xNlDN7UgPz61uCAxOTUvtSTeL8rc2MDS0szRmKACADbSMtI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease</title><source>esp@cenet</source><creator>Henry, Rodger F ; Ho, Raimundo ; Huang, Ye ; Dempah, Kassibla E ; Chan, Vincent S ; Cardinal-David, Benoit ; Wang, Zhi ; Zhang, Geoff G ; Stella, Valentino J ; Huters, Alexander D ; Krabbe, Scott W ; Lao, Yanbin ; Mayer, Peter T ; Enright, Brian P ; Lou, Xiaochun ; Mackey, Sean E ; Matulenko, Mark A ; Stambuli, James ; Miller, Christopher P ; Voight, Eric A ; Klix, Russell C ; Kym, Philip R</creator><creatorcontrib>Henry, Rodger F ; Ho, Raimundo ; Huang, Ye ; Dempah, Kassibla E ; Chan, Vincent S ; Cardinal-David, Benoit ; Wang, Zhi ; Zhang, Geoff G ; Stella, Valentino J ; Huters, Alexander D ; Krabbe, Scott W ; Lao, Yanbin ; Mayer, Peter T ; Enright, Brian P ; Lou, Xiaochun ; Mackey, Sean E ; Matulenko, Mark A ; Stambuli, James ; Miller, Christopher P ; Voight, Eric A ; Klix, Russell C ; Kym, Philip R</creatorcontrib><description>The present disclosure relates to pharmaceutical compositions comprising a phosphorylated carbidopa prodrug and a phosphorylated L-dopa prodrug, and the use thereof in the treatment of Parkinson's disease and associated conditions.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240426&DB=EPODOC&CC=NZ&NR=730996A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240426&DB=EPODOC&CC=NZ&NR=730996A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Henry, Rodger F</creatorcontrib><creatorcontrib>Ho, Raimundo</creatorcontrib><creatorcontrib>Huang, Ye</creatorcontrib><creatorcontrib>Dempah, Kassibla E</creatorcontrib><creatorcontrib>Chan, Vincent S</creatorcontrib><creatorcontrib>Cardinal-David, Benoit</creatorcontrib><creatorcontrib>Wang, Zhi</creatorcontrib><creatorcontrib>Zhang, Geoff G</creatorcontrib><creatorcontrib>Stella, Valentino J</creatorcontrib><creatorcontrib>Huters, Alexander D</creatorcontrib><creatorcontrib>Krabbe, Scott W</creatorcontrib><creatorcontrib>Lao, Yanbin</creatorcontrib><creatorcontrib>Mayer, Peter T</creatorcontrib><creatorcontrib>Enright, Brian P</creatorcontrib><creatorcontrib>Lou, Xiaochun</creatorcontrib><creatorcontrib>Mackey, Sean E</creatorcontrib><creatorcontrib>Matulenko, Mark A</creatorcontrib><creatorcontrib>Stambuli, James</creatorcontrib><creatorcontrib>Miller, Christopher P</creatorcontrib><creatorcontrib>Voight, Eric A</creatorcontrib><creatorcontrib>Klix, Russell C</creatorcontrib><creatorcontrib>Kym, Philip R</creatorcontrib><title>Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease</title><description>The present disclosure relates to pharmaceutical compositions comprising a phosphorylated carbidopa prodrug and a phosphorylated L-dopa prodrug, and the use thereof in the treatment of Parkinson's disease and associated conditions.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPBwTixKykzJL0hUSMxLUcjRBTMLivJTikrTi8FiJRmpmUUKpcWpCiX5CiVFqYklCgWJRdmZecX5eerFCimZxamJxak8DKxpiTnFqbxQmptBzs01xNlDN7UgPz61uCAxOTUvtSTeL8rc2MDS0szRmKACADbSMtI</recordid><startdate>20240426</startdate><enddate>20240426</enddate><creator>Henry, Rodger F</creator><creator>Ho, Raimundo</creator><creator>Huang, Ye</creator><creator>Dempah, Kassibla E</creator><creator>Chan, Vincent S</creator><creator>Cardinal-David, Benoit</creator><creator>Wang, Zhi</creator><creator>Zhang, Geoff G</creator><creator>Stella, Valentino J</creator><creator>Huters, Alexander D</creator><creator>Krabbe, Scott W</creator><creator>Lao, Yanbin</creator><creator>Mayer, Peter T</creator><creator>Enright, Brian P</creator><creator>Lou, Xiaochun</creator><creator>Mackey, Sean E</creator><creator>Matulenko, Mark A</creator><creator>Stambuli, James</creator><creator>Miller, Christopher P</creator><creator>Voight, Eric A</creator><creator>Klix, Russell C</creator><creator>Kym, Philip R</creator><scope>EVB</scope></search><sort><creationdate>20240426</creationdate><title>Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease</title><author>Henry, Rodger F ; Ho, Raimundo ; Huang, Ye ; Dempah, Kassibla E ; Chan, Vincent S ; Cardinal-David, Benoit ; Wang, Zhi ; Zhang, Geoff G ; Stella, Valentino J ; Huters, Alexander D ; Krabbe, Scott W ; Lao, Yanbin ; Mayer, Peter T ; Enright, Brian P ; Lou, Xiaochun ; Mackey, Sean E ; Matulenko, Mark A ; Stambuli, James ; Miller, Christopher P ; Voight, Eric A ; Klix, Russell C ; Kym, Philip R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NZ730996A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Henry, Rodger F</creatorcontrib><creatorcontrib>Ho, Raimundo</creatorcontrib><creatorcontrib>Huang, Ye</creatorcontrib><creatorcontrib>Dempah, Kassibla E</creatorcontrib><creatorcontrib>Chan, Vincent S</creatorcontrib><creatorcontrib>Cardinal-David, Benoit</creatorcontrib><creatorcontrib>Wang, Zhi</creatorcontrib><creatorcontrib>Zhang, Geoff G</creatorcontrib><creatorcontrib>Stella, Valentino J</creatorcontrib><creatorcontrib>Huters, Alexander D</creatorcontrib><creatorcontrib>Krabbe, Scott W</creatorcontrib><creatorcontrib>Lao, Yanbin</creatorcontrib><creatorcontrib>Mayer, Peter T</creatorcontrib><creatorcontrib>Enright, Brian P</creatorcontrib><creatorcontrib>Lou, Xiaochun</creatorcontrib><creatorcontrib>Mackey, Sean E</creatorcontrib><creatorcontrib>Matulenko, Mark A</creatorcontrib><creatorcontrib>Stambuli, James</creatorcontrib><creatorcontrib>Miller, Christopher P</creatorcontrib><creatorcontrib>Voight, Eric A</creatorcontrib><creatorcontrib>Klix, Russell C</creatorcontrib><creatorcontrib>Kym, Philip R</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Henry, Rodger F</au><au>Ho, Raimundo</au><au>Huang, Ye</au><au>Dempah, Kassibla E</au><au>Chan, Vincent S</au><au>Cardinal-David, Benoit</au><au>Wang, Zhi</au><au>Zhang, Geoff G</au><au>Stella, Valentino J</au><au>Huters, Alexander D</au><au>Krabbe, Scott W</au><au>Lao, Yanbin</au><au>Mayer, Peter T</au><au>Enright, Brian P</au><au>Lou, Xiaochun</au><au>Mackey, Sean E</au><au>Matulenko, Mark A</au><au>Stambuli, James</au><au>Miller, Christopher P</au><au>Voight, Eric A</au><au>Klix, Russell C</au><au>Kym, Philip R</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease</title><date>2024-04-26</date><risdate>2024</risdate><abstract>The present disclosure relates to pharmaceutical compositions comprising a phosphorylated carbidopa prodrug and a phosphorylated L-dopa prodrug, and the use thereof in the treatment of Parkinson's disease and associated conditions.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_NZ730996A |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T20%3A02%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Henry,%20Rodger%20F&rft.date=2024-04-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ENZ730996A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |