Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease

The present disclosure relates to pharmaceutical compositions comprising a phosphorylated carbidopa prodrug and a phosphorylated L-dopa prodrug, and the use thereof in the treatment of Parkinson's disease and associated conditions.

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Bibliographische Detailangaben
Hauptverfasser:	Henry, Rodger F, Ho, Raimundo, Huang, Ye, Dempah, Kassibla E, Chan, Vincent S, Cardinal-David, Benoit, Wang, Zhi, Zhang, Geoff G, Stella, Valentino J, Huters, Alexander D, Krabbe, Scott W, Lao, Yanbin, Mayer, Peter T, Enright, Brian P, Lou, Xiaochun, Mackey, Sean E, Matulenko, Mark A, Stambuli, James, Miller, Christopher P, Voight, Eric A, Klix, Russell C, Kym, Philip R
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure relates to pharmaceutical compositions comprising a phosphorylated carbidopa prodrug and a phosphorylated L-dopa prodrug, and the use thereof in the treatment of Parkinson's disease and associated conditions.