Substituted 2-azabicycles and their use as orexin receptor modulators

The present invention is directed to compounds of Formula (I) that are orexin receptor modulators, suitable for the treatment of mood disorders, stress-related disorders, attention deficit disorders, cognitive deficiencies, or substance abuse. Methods of making the compounds of Formula I are also de...

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Bibliographische Detailangaben
Hauptverfasser:	Chen, Gang, Lebold, Terry P, Ziff, Jeannie M, Coate, Heather R, Preville, Cathy, Shireman, Brock T, Dvorak, Curt A, Gelin, Christine F
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to compounds of Formula (I) that are orexin receptor modulators, suitable for the treatment of mood disorders, stress-related disorders, attention deficit disorders, cognitive deficiencies, or substance abuse. Methods of making the compounds of Formula I are also described. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of using the compounds of the invention are also within the scope of the invention.