Self-optimising respiratory therapy system

A computer-implemented method and system for evaluating use of a respiratory therapy device for treating a respiratory disorder of a patient, comprising: receiving, in one or more processors, input data relating to respiratory therapy delivered to the patient via the respiratory therapy device; computing, in the one or more processors, a success prediction score by applying a compliance model to the received input data, the success prediction score representing a success prediction regarding progress of the respiratory therapy, the success prediction score indicating a probability that the patient will be compliant with a predetermined compliance rule; evaluating, by the one or more processors, the success prediction score to trigger one or more communications concerning use of the respiratory therapy device; and transmitting a control command to adjust a setting of the respiratory therapy device based on the evaluation.