Bicyclic aza compounds as muscarinic m1 receptor and/or m4 receptor agonists

This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compound...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Tehan, Benjamin Gerald, Cansfield, Julie Elaine, Teobold, Barry John, Brown, Giles Albert, Pickworth, Mark, Rackham, Mark David, Congreve, Miles Stuart, O'brien, Michael Alistair
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula (1), or a salt thereof, wherein Q, R1 , R2, R3 and R4 are as defined herein.