Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use

The present invention relates to a combination comprising (a) a synaptic vesicle protein 2a ("SV2A") ligand selected from the group consisting of levetiracetam, brivaracetam and seletracetam; and (b) a positive allosteric modulator of the metabotropic glutamatergic receptor subtype 2 selec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	White, H, Trabanco-Suárez, Andrés, Klein, Brian, Van Osselaer, Nancy, Twyman, Roy, Cid-Núñez, José, Pype, Stefan, Ceusters, Marc André, Bone, Roger, Lavreysen, Hilde
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a combination comprising (a) a synaptic vesicle protein 2a ("SV2A") ligand selected from the group consisting of levetiracetam, brivaracetam and seletracetam; and (b) a positive allosteric modulator of the metabotropic glutamatergic receptor subtype 2 selected from a compound having a Formula as shown in the abstract drawing or a pharmaceutically acceptable salt or a solvate thereof.