Storage stable lyophilized tripeptide formulations
The invention relates to Lysyl-Prolyl-Threonine (KPT) lyophilized formulations, in particular to L-Lysyl-D-Prolyl-L-Threonine lyophilized formulations, that are stable in storage, and to a process for preparing the lyophilized formulations. The lyophilized formulation comprises KPT or a pharmaceutic...
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Zusammenfassung: | The invention relates to Lysyl-Prolyl-Threonine (KPT) lyophilized formulations, in particular to L-Lysyl-D-Prolyl-L-Threonine lyophilized formulations, that are stable in storage, and to a process for preparing the lyophilized formulations. The lyophilized formulation comprises KPT or a pharmaceutically acceptable salt thereof, a bulking agent trehalose and a buffering agent citric acid. Moreover, the invention relates to pharmaceutical and cosmetic compositions comprising the lyophilized formulations, that are used in the therapeutic and/or prophylactic treatment, diagnosis and/or therapy of pain-related diseases, pruritus-related diseases, inflammatory diseases, and/or other diseases in a mammal. |
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