Compounds and methods for inhibiting phosphate transport

Provided are non-NHE3-binding agents having activity as phosphate transport/uptake inhibitors in the gastrointestinal tract, including in the small intestine, methods for their use as therapeutic or prophylactic agents, and related methods of drug discovery.

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Bibliographische Detailangaben
Hauptverfasser: Jacobs, Jeffrey W, Charmot, Dominique, Carreras, Christopher, Langsetmo, Ingrid, Lewis, Jason
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are non-NHE3-binding agents having activity as phosphate transport/uptake inhibitors in the gastrointestinal tract, including in the small intestine, methods for their use as therapeutic or prophylactic agents, and related methods of drug discovery.