Trk-inhibiting compound

The invention provides a drug having as the active ingredient a compound having Trk-inhibiting activity in the prevention and/or treatment of Trk-associated diseases, for example, pain, pruritus, lower urinary tract disorders, asthma, allergic rhinitis, inflammatory bowel disease, Chagas disease, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Takeuchi, Jun, Ikura, Masahiro, Higashino, Masato, Nagaura, Takeshi, Yasuhiro, Tetsuya, Itadani, Satoshi, Hashimura, Kazuya
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides a drug having as the active ingredient a compound having Trk-inhibiting activity in the prevention and/or treatment of Trk-associated diseases, for example, pain, pruritus, lower urinary tract disorders, asthma, allergic rhinitis, inflammatory bowel disease, Chagas disease, and the like. A compound shown by general formula (I) (in the formula, all symbols represent the same meanings as the symbols in the specification), a salt thereof, N-oxide thereof, solvate thereof, or a prodrug of these is useful as a drug component having Trk-inhibiting activity in the prevention and/or treatment of pain, pruritus, lower urinary tract disorders, asthma, allergic rhinitis, inflammatory bowel disease, Chagas disease, and other such conditions.