C1-inh compositions and methods for the prevention and treatment of disorders associated with c1 esterase inhibitor deficiency

C1-inh compositions and methods for the prevention and treatment of disorders associated with c1 esterase inhibitor deficiency

Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency, such as hereditary angioedema (HAE), via subcutaneous administration, wherein the compositions comprise a C1 esterase inhibitor between 400 to 600 U/mL, a citrate or phosphate...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Manning, Mark, Ruddy, Steven, Gallagher, Cynthia
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency, such as hereditary angioedema (HAE), via subcutaneous administration, wherein the compositions comprise a C1 esterase inhibitor between 400 to 600 U/mL, a citrate or phosphate buffer, a pH in the range of 6.5 to 8.