Solid state forms of a quinazoline derivative and its use as a braf inhibitor

Solid state forms of a quinazoline derivative and its use as a braf inhibitor

This application relates to various salts and solid state forms (including the free base form) of Compound (I). This application also relates to pharmaceutical compositions and therapeutic uses of these materials and compositions. In one embodiment, the application relates to uses of a crystalline f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bierlmaier Stephen J, Jacobs Martin J, Haltiwanger Ralph C
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This application relates to various salts and solid state forms (including the free base form) of Compound (I). This application also relates to pharmaceutical compositions and therapeutic uses of these materials and compositions. In one embodiment, the application relates to uses of a crystalline form of Compound (I) for treating cancer, such as melanoma, colorectal cancer, papillary thyroid carcinoma, ovarian cancer and/or non-small cell lung cancer.