Time released biodegradable or bioerodible microspheres or microparticles suspended in a solidifying depot-forming injectable drug formulation

The disclosure relates to a composite drug delivery material comprising a plurality of microparticles dispersed in a media composition; wherein the microparticles comprise: a drug; and a coating comprising a bioerodible material or a biodegradable material; and wherein the media composition comprises the drug dispersed in a depot forming material; and wherein the media composition is in a liquid form before administration and is configured to substantially increase in viscosity during or after being injected into a body of a mammal, so that the form of the media after injection is a solid or a gel. The disclosure also relates to the use of these in treating an ocular disease or injury.