Combination therapy for the treatment of ocular neovascular disorders

Disclosed is a pharmaceutical combination comprising: (i) a PDGF antagonist that is an antibody or binding fragment thereof; and (ii) a VEGF antagonist that is an aptamer; and wherein the PDGF antagonist and VEGF antagonist are formulated for sequential or simultaneous administration to a patient.

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Bibliographische Detailangaben
Hauptverfasser:	ADAMIS ANTHONY P, CALIAS PERRY, SHIMA DAVID
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed is a pharmaceutical combination comprising: (i) a PDGF antagonist that is an antibody or binding fragment thereof; and (ii) a VEGF antagonist that is an aptamer; and wherein the PDGF antagonist and VEGF antagonist are formulated for sequential or simultaneous administration to a patient.