Caprylate viral deactivation

Patent No. 613554 Disclosed is a method of preparing albumin from a solution comprising albumin comprising: adjusting the protein concentration of the solution to less than about 5wt%; adjusting pH of the solution to about pH 5 or less; adding caprylic acid (octanoic acid) or sodium caprylate; raisi...

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Bibliographische Detailangaben
Hauptverfasser: HOTTA JOANN, LEBING WYTOLD, ROTH NATHAN, BURNS DOUG
Format: Patent
Sprache:eng
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Zusammenfassung:Patent No. 613554 Disclosed is a method of preparing albumin from a solution comprising albumin comprising: adjusting the protein concentration of the solution to less than about 5wt%; adjusting pH of the solution to about pH 5 or less; adding caprylic acid (octanoic acid) or sodium caprylate; raising the solution temperature greater than about 20 °C; and incubating the solution for about 30 min to about 120 min.