Phenyl-isoxazol derivatives and preparation process thereof
Disclosed are a range of piperidine and piperazine phenyl-isoxazol derivatives of formula I for example (4-(3,4-dichlorophenyl)piperazine-1-yl)(3-(3-fluorophenyl)-5-methylisoxazol-4-yl)methanone and ethyl-1-(5-amino-3-(2-chlorophenyl)isoxazol-4-carbonyl)piperidine-4-carboxylate, and pharmaceutical c...
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creator | CHO DAE JIN KIM HONG YOUB LEE GONG YEAL LEE HAE UN AHN CHOONG AM KIM SUNG MOO WOO SEOK HUN YOON SEUNG BIN KIM DONG YEON |
description | Disclosed are a range of piperidine and piperazine phenyl-isoxazol derivatives of formula I for example (4-(3,4-dichlorophenyl)piperazine-1-yl)(3-(3-fluorophenyl)-5-methylisoxazol-4-yl)methanone and ethyl-1-(5-amino-3-(2-chlorophenyl)isoxazol-4-carbonyl)piperidine-4-carboxylate, and pharmaceutical compositions thereof, which are intended for the treatment of viral infection, especially, infection of an influenza virus. Also disclosed are preparation methods for the compounds. |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Phenyl-isoxazol derivatives and preparation process thereof |
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