Phenyl-isoxazol derivatives and preparation process thereof

Phenyl-isoxazol derivatives and preparation process thereof

Disclosed are a range of piperidine and piperazine phenyl-isoxazol derivatives of formula I for example (4-(3,4-dichlorophenyl)piperazine-1-yl)(3-(3-fluorophenyl)-5-methylisoxazol-4-yl)methanone and ethyl-1-(5-amino-3-(2-chlorophenyl)isoxazol-4-carbonyl)piperidine-4-carboxylate, and pharmaceutical c...

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Bibliographische Detailangaben
Hauptverfasser: CHO DAE JIN, KIM HONG YOUB, LEE GONG YEAL, LEE HAE UN, AHN CHOONG AM, KIM SUNG MOO, WOO SEOK HUN, YOON SEUNG BIN, KIM DONG YEON
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed are a range of piperidine and piperazine phenyl-isoxazol derivatives of formula I for example (4-(3,4-dichlorophenyl)piperazine-1-yl)(3-(3-fluorophenyl)-5-methylisoxazol-4-yl)methanone and ethyl-1-(5-amino-3-(2-chlorophenyl)isoxazol-4-carbonyl)piperidine-4-carboxylate, and pharmaceutical compositions thereof, which are intended for the treatment of viral infection, especially, infection of an influenza virus. Also disclosed are preparation methods for the compounds.