Compositions comprising a pi3k inhibitor and a mek inhibitor and their use for treating cancer

Compositions comprising a pi3k inhibitor and a mek inhibitor and their use for treating cancer

Disclosed is a composition comprising a MEK inhibitor compound of formula (I) (also known as MSC1936369 or AS703026 or MSC6369) and a PI3K inhibitor compound of either formula (2a) (also known as XL147 or SAR245408) or formula (2b) (also known as XL765, SAR245409 or MSC0765). The compositions are us...

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Bibliographische Detailangaben
Hauptverfasser: VINCENT LOIC, MA JIANGUO, DEBUSSCHE LAURENT, GARCIA-ESCHEVERRIA CARLOS, OGDEN JANET ANNE MEURER, MCMILLAN STUART
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed is a composition comprising a MEK inhibitor compound of formula (I) (also known as MSC1936369 or AS703026 or MSC6369) and a PI3K inhibitor compound of either formula (2a) (also known as XL147 or SAR245408) or formula (2b) (also known as XL765, SAR245409 or MSC0765). The compositions are useful in the treatment of cancer and reducing tumour size.