Naphth-2-ylacetic acid derivatives to treat aids

Disclosed herein are compounds of formula (Ib): or a salt thereof as described herein. Also disclosed are pharmaceutical compositions comprising a compound of formula (Ib), processes for preparing compounds of formula (Ib), intermediates useful for preparing compounds of formula (Ib) and therapeutic...

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Bibliographische Detailangaben
Hauptverfasser:	GUO HONGYAN, LINK JOHN O, BACON ELIZABETH, VIVIAN RANDALL W, HRVATIN PAUL, ROETHLE PAUL, TAYLOR JAMES, LIU HONGTAO, XU LIANHONG, MITCHELL MICHAEL L, TRENKLE JAMES D, BJORNSON KYLA, MCFADDEN RYAN, BABAOGLU KERIM, HALCOMB RANDALL L
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed herein are compounds of formula (Ib): or a salt thereof as described herein. Also disclosed are pharmaceutical compositions comprising a compound of formula (Ib), processes for preparing compounds of formula (Ib), intermediates useful for preparing compounds of formula (Ib) and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula (Ib). An example of a compound of formula (Ib) is: 2-tert-butoxy-2-(1-(4-chlorophenyl)-3-methyl-5-(pyrimidin-5-yl)naphthalen-2-yl)acetic acid