Biodegradable polymer - bioactive moiety conjugates

Disclosed is a biodegradable polymer comprising a polyester component, the biodegradable polymer prepared by polymerising a diol monomer - bioactive moiety conjugate of formula (II) with at least one selected from the group consisting of: (i) an alkyl ester of lysine diisocyanate; and (ii) a polyiso...

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Bibliographische Detailangaben
Hauptverfasser: O'SHEA MICHAEL SHANE, JEFFERY JUSTINE LEIGH, GRAICHEN FLORIAN HANS MAXIMILIAN, TAING HENG CHY, TAIT RUSSELL JOHN
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed is a biodegradable polymer comprising a polyester component, the biodegradable polymer prepared by polymerising a diol monomer - bioactive moiety conjugate of formula (II) with at least one selected from the group consisting of: (i) an alkyl ester of lysine diisocyanate; and (ii) a polyisocyanate in the presence of one or more polyester polyol co-monomers, wherein the variables X', Y', R, Z and D are as defined in the specification.