Amine derivative compounds for treating ophthalmic diseases and disorders

601573 Disclosed is a aryl alkylamine or aryl alkoxyamine of formula (A) where the variable are as disclosed in the specification. Examples of compounds of formula (A) are: 4-(3-(3-aminopropoxy)phenylethyl)heptan-4-ol; 4-(3-(3-aminopropoxy)-5-methoxyphenylethyl)heptan-4-ol; 3-(3-(3-aminopropyl)pheny...

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Hauptverfasser: KUBOTA RYO, ORME MARK W, HONG FENG, KUKSA VLADIMIR A, SCOTT IAN L, LITTLE THOMAS L. JR
Format: Patent
Sprache:eng
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Zusammenfassung:601573 Disclosed is a aryl alkylamine or aryl alkoxyamine of formula (A) where the variable are as disclosed in the specification. Examples of compounds of formula (A) are: 4-(3-(3-aminopropoxy)phenylethyl)heptan-4-ol; 4-(3-(3-aminopropoxy)-5-methoxyphenylethyl)heptan-4-ol; 3-(3-(3-aminopropyl)phenyl)-2,2-dimethylpropyl acetate and 1-(3-(3-amino-1-hydroxypropyl)phenyl)hexan-3-ol. Also disclosed is a pharmaceutical composition and the use of a compound of formula (A) in the preparation of a medicament for the treatment of ophthalmic disease or disorder in a subject.