CHEMICAL COMPOUNDS for treating Hepatitis C virus

Patent No. 597982 Disclosed is a compound of formula I; wherein each R1 is independently H or C1-3 alkyl; each R2 is independently C1-3 alkyl; each X is independently CRR, O or S; n is 2 or 3; and each R is independently methyl, hydrogen or deuterium, such as methyl [(1S)-2-methyl-1-({ (2S)-2-[4-(4&...

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Hauptverfasser: GRIMES, RICHARD, MARTIN, COUCH, RICKY, KAZMIERSKI, WIESLAW, MIECZYSLAW, NORTON, BETH, ADAMS, DUAN, MAOSHENG, CHEN, PINGYUN, TALLANT, MATTHEW
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Sprache:eng
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Zusammenfassung:Patent No. 597982 Disclosed is a compound of formula I; wherein each R1 is independently H or C1-3 alkyl; each R2 is independently C1-3 alkyl; each X is independently CRR, O or S; n is 2 or 3; and each R is independently methyl, hydrogen or deuterium, such as methyl [(1S)-2-methyl-1-({ (2S)-2-[4-(4'-{ 2-[(8S)-7-((2S)-3-methyl-2-{ [(methyloxy)carbonyl]amino} butanoyl)-1,4-dioxa-7-azaspiro[4.4]non-8-yl]-1 H-imidazol- 4-yl} -4-biphenylyl)-1H-imidazol-2-yl]-1-pyrrolidinyl} carbonyl)propyl]carbamate.