HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING

Patent No. 596723 Disclosed is an isolated human antibody, or antigen-binding portion thereof, that neutralizes the activity of human IL-12 and at least one additional primate IL-12 selected from the group consisting of baboon IL-12, marmoset IL-12, chimpanzee IL-12, cynomolgus IL-12 and rhesus IL-1...

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Hauptverfasser:	MYLES, ANGELA, CARMEN, SARA, SALFELD, JOCHEN G, BANERJEE, SUBHASHIS, WARNE, NICHOLAS W, SMITH, STEPHEN, FRIEDRICH, STUART, DU FOU, SARAH L, ELVIN, JOHN G, LABKOVSKY, BORIS, VENTURINI, AMY, DERBYSHIRE, ELAINE J, KAYMAKCALAN, ZEHRA, HOLTET, THOR LAS, PASKIND, MICHAEL, WIDOM, ANGELA, WHITE, MICHAEL, DUNCAN, ALEXANDER R, TRACEY, DANIEL E, SAKORAFAS, PAUL, VELDMAN, GEERTRUIDA M, ROGUSKA, MICHAEL
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Zusammenfassung:	Patent No. 596723 Disclosed is an isolated human antibody, or antigen-binding portion thereof, that neutralizes the activity of human IL-12 and at least one additional primate IL-12 selected from the group consisting of baboon IL-12, marmoset IL-12, chimpanzee IL-12, cynomolgus IL-12 and rhesus IL-12, but which does not neutralize the activity of mouse IL-12.